Specter of a new bond appears

A new type of hydrogen bond that forms between a B-H group and an aromatic ring has been discovered by Dieter Cremer and Wenli Zou of the computational and theoretical chemistry group at Southern Methodist University, Dallas in the US. Relatively weak non-covalent bonds between aromatic rings and a hydrogen atom joined to a carbon, nitrogen or oxygen atom, are common and critical in molecular biology and supramolecular chemistry but hints of a new approach to drug design might now be possible thanks to the discovery of the novel B-H…Pi ring hydrogen bond.