Malaria revelations

Scientists in Sweden have laid bare the structure and function of a new enzyme from the malaria parasite, Plasmodium falciparum. Johan Åqvist and doctoral student Sinisa Bjelic working under the umbrella of the RAPID project at the Uppsala University Center for Structural Biology, Medical Chemistry, and Computer Chemistry, studied the previously unknown enzyme, which is of a new class. Knowing its structure and function will lead to a new target for drug discovery against this killer disease at a time when new drug leads against malaria are desperately needed because of emerging parasite resistance.