Grape skin against sickle cell

Medical College of Georgia researchers say that a polyphenol extracted from grape skin looks promising as a novel treatment for sickle cell anemia. Resveratrol has been found to induce production of fetal hemoglobin, which decreases the "sickling" of red blood cells and reduces the painful vascular episodes associated with the disease, according to Davies Agyekum and colleagues. The anticancer agent hydroxyurea has shown similar benefits, but Agyekum suggests that therapy based on resveratrol might be "easier" on patients and have fewer side effects.