A gel containing nitroglycerine could soon become an over-the-counter treatment for erectile dysfunction according to Futura Medical and GlaxoSmithkline. The compound, more commonly known in medical circles as glyceryl trinitrate, has been prescribed for angina for many years. The recent flurry of interest in this and related compounds for treating sexual dysfunction has led to a focus on such vasodilators. Now, Futura and GSK hope to enlist volunteers to test a gel containing GTN for the topical treatment of impotence. They anticipate receiving regulatory approval in 2008. They are also going to assess the effects of the gel on the female partners of the volunteers. It is well known that nitroglycerine can cause headaches, which would not be a positive outcome for the male volunteers cured of their dysfunction.