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Chemistry
How Mutation Causes Alzheimer's Disease  May 12, 2008

"It is a really tiny change but it has tremendous consequences"

Your fate can be determined by tiny events. Imagine you live in the city and you walk everywhere to get exercise - ' you are healthy and not afraid of getting mugged. via EMaxHealth

Mechanism Uncovered Of Action Of Antibiotic Able To Reduce Neuronal Cell Death In Brain  May 12, 2008

"This work not only has implications for the field of neurodegeneration and neurobiology, but may also help us more clearly understand brain cancer, including malignant glioma, an invariably fatal tumor, and how it impacts brain function"

Main Category: Neurology / Neuroscience Also Included In: Alzheimer's / Dementia Stroke / Neuroprotection Research Highlights: Mechanism of action of compound found to induce neurotransmitter activity in brain ... via MediLexicon

Notes from School  May 12, 2008

Three organic chemistry students from University of Wisconsin-Fond du Lac will present their semester-long research findings at 6 p.m. Tuesday, May 13, in the large group instruction room of UW-Fond du Lac, 400 ... via Fond du Lac Reporter

New Chemicals Shield - Genome Guardian'  May 11, 2008

Cancer Research UK scientists have discovered a potent group of chemicals that protect p53 a major anti-tumour gene from destruction, a study published in Cancer Cell* today reveals. via Med Ad News

Ask Dr. Gott: Explore options for sugar substitutes  May 11, 2008

DEAR DR. GOTT: I am a former professor of analytic chemistry who taught at a major university in Florida. via Hometown Annapolis

Pharmacology and Medicine
Biology
New Discovery On Role Of Vital Protein That Fights Meningitus 
A University of Leicester researcher has discovered how a protein in the blood linked to defence against meningitis plays a more vital role than previously understood in the body's immune defence system.The published research has helped to advance medical understanding of how the body defends against disease and heals itself.
Fruit Fly Avoidance Mechanism Could Lead To New Ways To Control Pain In Humans 
At first, fruit flies eat like horses. Hatching inside over-ripe fruit where they were laid, they feed wildly in the sugar-rich environment until nature sends them an offer they can't refuse. To survive, they must leave the fruit, wander off and burrow into the earth where they avoid food as if it were poison. Only then can the larvae grow and hatch into flies that will take wing to lay their own eggs.
Evidence Discovered For Suspected Cause Of Type 1 Diabetes 
Scientists at Washington University School of Medicine in St. Louis working with diabetic mice have examined in unprecedented detail the immune cells long thought to be responsible for type 1 diabetes.Researchers were able to examine the immune cells from isolated insulin-making structures in the pancreas known as the islets of Langerhans.
International Study Discovers 10 New Genes Related To Human Growth 
This meta-analysis, published in the latest issue of Nature Genetics, is based on data from more than 26,000 study participants. It verifies two already known genes, but also discovered ten new genes. Altogether they explain a difference in body size of about 3.5 centimeters.The analysis produced some biologically insightful findings. Several of the identified genes are targeted by the microRNA let-7, which affects the regulation of other genes.
Studying Regulation Of Genes To Understand The Underpinnings Of Most Human Diseases 
A team of scientists has provided, for the first time, a detailed map of how the building blocks of chromosomes, the cellular structures that contain genes, are organized in the fruit fly Drosophila melanogaster. The work identifies a critical stop sign for transcription, the first step in gene expression, and has implications for understanding how the AIDS virus regulates its genes. The findings will be published in the 15 May 2008 issue of the journal Nature.
Materials
Nanotubes Functionalized Controllably 
Method relies on electochemistry, conductance.
Assessing Nanotech Exposure 
The National Institute for Occupational Safety & Health is seeking input on its interim guidance for the medical screening of workers exposed to engineered nanoparticles.
New Journal Editor 
Penn State's Paul S. Weiss will lead ACS Nano.
Molecules' Open Arms Influence Nanoshapes 
A nanoparticle's shape and size can influence its properties just as much as its chemistry.
Constructing The Gilded Cage 
Dendritic growth creates hardier platinum nanocages.
Companies
STN Public Training Schedule 
Latest STN e-Seminar and public workshop schedule
Core Journal Coverage List Updated - February 2008 
The list of core journal coverage in the CAplus database was updated on February 29, 2008
CAS and Bob Massie Honored at People of Vision Award Dinner 
Chemical Abstracts Service and President Robert J. Massie were recognized for outstanding community service and philanthropic vision at Prevent Blindness Ohio's 23rd annual People of Vision Award Dinner on March 4, 2008
2008 STN Price List 
The comprehensive 2008 STN price list is now online
Customer Quotes on Value of CAS 
Customer comments on the value of CAS and its products
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